Clinical investigations into ulcerative colitis: Advancements and discoveries
New Clinical Trials Offer Hope for Ulcerative Colitis Sufferers
Ulcerative colitis (UC) patients are now presented with a variety of clinical trials testing new biologic therapies and treatments, aimed at inducing and maintaining remission in both pediatric and adult populations. These trials, which can last over a year and involve multiple visits, are currently underway and actively recruiting patients.
One such study is comparing infliximab with corticosteroids as a primary therapy for moderate to severe UC. Another notable trial is the comparison between vedolizumab and adalimumab for the treatment of moderate to severe UC, which showed that vedolizumab was more effective for clinical remission and endoscopic improvement in a 2019 study. The FDA has approved vedolizumab as a treatment for UC, under the brand name Entyvio.
Bristol Myers Squibb recently completed a study for a new medication to treat UC, using BMS-986165. Additionally, there is a study observing VE202, a live biotherapeutic product for mild to moderate UC, which is open to individuals aged 18-75 years.
For those interested in participating in these trials, reliable online resources include ClinicalTrials.gov, academic medical centers' trial databases, and local clinical trial recruiting websites. By using these resources, you can locate trials recruiting UC patients near you and review eligibility criteria and contact information.
It is also beneficial to discuss your interest in clinical trials with your gastroenterologist or specialist in inflammatory bowel disease. They can help identify suitable studies based on your disease severity, age, and medical history, and facilitate referrals to sites conducting the trials. Your doctor may already be involved in research or have direct access to trial coordinators.
Before signing up for a clinical trial, it is essential to consider factors such as costs, safety, follow-up care, personal outcome, eligibility, main purpose, researchers' expectations, effects on regular healthcare routines, and the trial's purpose. Understanding the trial design, risks, benefits, and commitments is crucial before consenting.
These ongoing clinical trials for UC are guided by recent FDA and EMA updated recommendations to enhance safety, inclusivity, and standardized efficacy measures, which improves the quality of these studies and benefits participants.
By combining online search tools with your healthcare provider's support, you can find and join clinical trials that may provide access to new therapies and contribute to UC research advances.
- Ulcerative colitis (UC) seekers can now explore a multitude of clinical trials, testing novel biologic therapies and treatments intended to induce and maintain remission in both pediatric and adult populations.
- One such trial is comparing infliximab with corticosteroids as primary therapy for moderate to severe UC, while another notable study compares vedolizumab and adalimumab for the treatment of the same, with vedolizumab showing more effectiveness.
- Bristol Myers Squibb completed a study for a new UC medication using BMS-986165, and there's an observational study open for VE202, a live biotherapeutic product for mild to moderate UC.
- Ulcerative colitis patients interested in participating in these trials can utilize online resources like ClinicalTrials.gov, academic medical centers' trial databases, and local clinical trial recruiting websites.
- It's advantageous to discuss your interest in clinical trials with your gastroenterologist or inflammatory bowel disease specialist, who can identify suitable studies based on your disease severity, age, and medical history.
- Before signing up for a clinical trial, consider factors like costs, safety, follow-up care, personal outcome, eligibility, main purpose, researchers' expectations, effects on regular healthcare routines, and the trial's purpose carefully.
- These ongoing UC clinical trials are guided by recent FDA and EMA updated recommendations to improve safety, inclusivity, and standardized efficacy measures, which increases the quality of these studies and benefits participants.
- By combining online search tools with your healthcare provider's support, you can find and join clinical trials that may provide access to new therapies and contribute to ulcerative colitis research advances, potentially managing chronic diseases like cancer, fostering health and wellness, mental health, fitness and exercise, and various nutrition aspects.
