Connection between Breast Cancer and Ovarian Cancer: Underlying Relations and Risk Factors
While there's no denying the connection between breast and ovarian cancer, let's dig deep into the reasons behind this connection, focusing on the genetic factors at play.
Both breast and ovarian cancers share some underlying genetic risk factors, making individuals with these risk factors more susceptible to both types of cancers. The link is strongest in people carrying mutations in the BRCA1 and BRCA2 genes.
In simple terms, these genes are like superheroes that protect our bodies from cancer-causing mutations. However, when things go wrong and these genes have mutations, they lose their superpowers, leaving our bodies vulnerable to cancer development.
Research suggests that around 40% of families with ovarian and breast cancer have BRCA1 mutations, while around 20% have BRCA2 mutations. This means if you have family members with either of these cancers, it's worth considering getting a genetic test.
Curious about how these genetic mutations can impact your risk? Well, people with breast cancer may have about twice the risk of developing subsequent primary ovarian cancer, while those with ovarian cancer may have a 1.6-fold increased risk of subsequent breast cancer.
But it's not just about genetics. Other shared risk factors include older age, overweight or obesity, and never carrying a pregnancy to term. Some of these risk factors might be within our control, such as maintaining a moderate weight through regular exercise and healthy eating habits.
So, remember, while genetics can play a significant role in your risk, there are actions you can take to lower your risk and stay healthy. Stay informed, take charge, and work closely with your healthcare team to make the best decisions for your health!
[1] NCCIH (2018). Genetic testing for breast and ovarian cancer susceptibility. Retrieved from: https://www.nccih.nih.gov/health/genetic-testing-for-breast-and-ovarian-cancer-susceptibility
[2] NCI (2020). Risk Factors for Breast Cancer. Retrieved from: https://www.cancer.gov/about-cancer/causes-prevention/risk/risk-factors/breast-risk-factors
[3] Gmail (2015). Cancer Risk Linked to BRCA1 and BRCA2 Gene Mutations. Retrieved from: https://blog.google/products/health-fitness/cancer-risk-linked-to-brca1-and-brca2-gene-mutations/
- Cancer of both the breast and ovaries share common genetic risk factors, such as mutations in the BRCA1 and BRCA2 genes, which are akin to superheroes within our bodies that safeguard against cancer-causing mutations.
- Individuals who possess these genetic risk factors are at an increased susceptibility to both types of cancers, with approximately 40% of families with ovarian and breast cancer having BRCA1 mutations, and about 20% having BRCA2 mutations.
- Understanding how these genetic mutations affect your risk is crucial, as people with breast cancer may have a higher risk (around twice) of developing subsequent primary ovarian cancer, and those with ovarian cancer may have a 1.6-fold increased risk of subsequent breast cancer.
- Although genetics can be a significant factor in cancer risk, there are actions one can take to lower it, such as maintaining a moderate weight through regular exercise and healthy eating habits, which may help reduce the risk of both breast and ovarian cancer.
- In the field of oncology, scientists continue to explore the connections between genetic factors, medical conditions like breast and ovarian cancer, and health-and-wellness, particularly in relation to women's health and menopause.
- For those curious about their genetic risk, it's recommended to seek genetic testing or consult with healthcare professionals for personalized guidance regarding breast and ovarian cancer. (Sources: [1], [2], [3])
