Cost, effects, applications, and dosage details on Voranigo medication
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Helloo there! Let's talk about Voranigo, a brand name oral tablet for treating a specific type of brain tumors. It's all about that active ingredient vorasidenib, buddy!
The Food and Drug Administration (FDA) has given the green light to use Voranigo for treating grade 2 astrocytomas and oligodendrogliomas in both adults and kids aged 12 years and up. These are some special brain tumors, and Voranigo comes into play when they've got a special mutation that we call IDH1 or IDH2. Keep reading to learn more!
Drug deets
Here's the lowdown on Voranigo:
- Drug class: It’s a type of targeted cancer therapy, blocking those pesky IDH1 and IDH2 enzymes gone rogue in brain tumor cells, helping slow down their growth.
- Generic available? Nah, treat this one like a celeb - it's got no generic suitors yet.
- Prescription required? Absolutely, mates! You'll need a doc's script to snag some.
- Controlled substance? Nah, not that kind of control.
Know the Voranigo generic
As of now, Voranigo is flying solo with its brand name, baby. There ain’t no generic counterpart to snag at the pharmacy.
A generic drug is a doppelganger of the active ingredient in a brand-name medication. Generics generally cost less than brand names.
Cost and coupons, oh my!
Variety is the spice of life, even when it comes to drug costs! The actual amount you fork out depends on your insurance, location, and which pharmacy you choose.
less than 40 kg (about 88 pounds [lb])
Hey, financially struggling, or insurance-befuddled peeps! There’s help at hand! Call the ServierONE program at 800-813-5905 or pay a visit to their website to snag some financial support or learn more about your coverage.
Side effects, oh boy!
20 mg once per day
Voranigo can give you a case of the cringes, ranging from mild to serious. Here’s a rundown of the key side effects:
- Mild side effects: They can include fatigue, achy head, queasy stomach, runny dookies, constipation, reduced appetite, muscle or joint pain, COVID-19, lower white blood cell count, or a spike in liver enzymes.
- Serious side effects: These rarer side effects can be downright intense. Call your doc right away if you experience liver problems (yellow eyes or skin, stomach pain, loss of appetite, or dark-colored pee) or seizures (staring, quick blinking, sudden body stiffness, jerking movements, or loss of consciousness).
Got side effects? Spill the bean to the FDA!
After the FDA approves a drug, they keep a close eye on side effects in the wild. Reporting yours helps safer meds for everyone in the long run. If you develop a side effect and want to tell the FDA about it, visit MedWatch or dial 800-FDA-1088.
40 kg or more
Purpose in life: treating brain tumors
Voranigo is FDA-approved for treating a specific type of brain tumors – the grade 2 astrocytomas and oligodendrogliomas. Yep, we just called 'em brain tumors. Here's the lowdown:
40 mg once per day
- Those tumors belong to a group of brain tumors called gliomas.
- Astrocytomas: Tumors that start in astrocytes, brain cells that help provide support and nourishment to nerve cells.
- Oligodendrogliomas: Tumors that start in oligodendrocytes, brain cells that make a fatty substance called myelin that helps repair and support nerve cells.
Grade 2 brain tumors are slower-growing but can still invade nearby tissue. Voranigo attacks the IDH1 or IDH2 mutated tumors – your doc'll take a biopsy or sample to see if your tumor fits the bill.
Symptoms of grade 2 brain tumors may include morning headaches, nausea and vomit, changes in vision, hearing, or speech, balance problems, weakness or numbness on one side, changes in behavior, or seizures.
Riding the Voranigo dose train
Your doctor will decide the best dosage for your unique bod. Here are some general guidelines for dosing:
- Oral tablet: Voranigo comes in two forms – 10 milligrams (mg) and 40 mg.
- When to take: Once a day, set a reminder and stick to it!
- Dose skipping: If you miss a dose and it's been 6 hours or less, pop that pill now. If it's been more than 6 hours, skip it and pick up where you left off at your regular time. No double dosing, mate!
- Food: Pop that tablet with or without food. Your call, buddy!
- Lengthy usage: Voranigo is meant to be a long-term treatment. If it works for you and your doc gives the green light, you'll likely be on it for the long haul.
Q: Can Voranigo treat glioblastoma?A: Nope, Voranigo is not approved for treating glioblastoma.
Q: Is Voranigo chemotherapy?A: Nah, Voranigo is not chemo. It’s a targeted cancer therapy instead.
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
Remember: Medical News Today encourages you to consult with a licensed healthcare professional before taking any medications. This article does not serve as medical advice. Safety first, matey!
- Voranigo, a brand name oral tablet, is approved by the FDA for treating grade 2 astrocytomas and oligodendrogliomas, which are specific types of brain tumors that have a special IDH1 or IDH2 mutation.
- Voranigo is a targeted cancer therapy that blocks the IDH1 and IDH2 enzymes in brain tumor cells, helping to slow down their growth.
- As of now, there is no generic version of Voranigo available at pharmacies.
- The cost of Voranigo depends on factors such as insurance, location, and the chosen pharmacy. Financial assistance may be available through the ServierONE program for those in need.
- Side effects of Voranigo can range from mild to serious and may include fatigue, headache, nausea, changes in bowel movements, reduced appetite, and liver problems or seizures in rare cases.
- Voranigo is not a chemotherapy, nor is it approved for treating glioblastoma. Medications such as ciprofloxacin, cyclosporine, fluvoxamine, phenytoin, and hormonal forms of birth control may interact with Voranigo.
- When taking Voranigo, it is important to follow the prescribed dosage and consult with a licensed healthcare professional to ensure safety and optimal health-and-wellness outcomes.
