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High HDL 'Good' Cholesterol May Not Always Protect Against Heart Disease

High HDL levels usually mean lower heart disease risk. But new findings show this might not always be the case, particularly for those with high C-reactive protein levels.

This picture contains a rose flower which is in pink color. In the background, it is yellow in...
This picture contains a rose flower which is in pink color. In the background, it is yellow in color and it is blurred.

High HDL 'Good' Cholesterol May Not Always Protect Against Heart Disease

HDL cholesterol, often dubbed 'good' cholesterol, plays a crucial role in removing harmful cholesterol from the blood. However, recent research suggests that very high HDL levels may not always protect against heart disease, particularly in individuals with high C-reactive protein levels.

HDL levels above 60 mg/dL are typically recommended by doctors. Levels between 40 to 59 mg/dL are considered normal but improvable, while levels under 40 mg/dL increase heart disease risk. However, a study found that high HDL levels in people with high C-reactive proteins after a heart attack may not provide the expected protection and could even increase their risk of heart disease.

Factors such as recent illness, pregnancy, stress, or not fasting before the test can affect HDL test results. Maintaining overall cholesterol levels through lifestyle measures like not smoking, moderate alcohol consumption, regular exercise, and a low saturated fat diet is vital. A blood test determines HDL levels, with results usually taking a few days to process.

While high HDL levels generally indicate a lower risk of heart disease, recent research suggests that very high HDL levels may not always provide protection, especially in individuals with high C-reactive protein levels. Further studies are needed to fully understand these complex relationships and guide healthcare professionals in interpreting HDL levels.

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