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Organ donation: Should the system be based on implied consent or explicit consent?

Organ Donation: Should It Be a Default Option or Required Decision?

A fresh patient is enrolled in the organ transplant queue every 10 minutes within the United...
A fresh patient is enrolled in the organ transplant queue every 10 minutes within the United States.

Countries around the globe have different approaches to organ donation, prompting a debate over whether an opt-in or opt-out system is more effective. A team of researchers from the University of Nottingham, University of Stirling, and Northumbria University in the UK analyzed the donation protocols of 48 nations to determine which approach yields the best results.

In opt-in systems, individuals must actively register to donate their organs after death. In contrast, opt-out systems assume consent for organ donation, with individuals required to specifically request that their organs not be taken.

Prof. Eamonn Ferguson, the study's lead author from the University of Nottingham, acknowledges the drawbacks of relying on active decisions from individuals, as procrastination, loss aversion, and faith in government decisions can hinder registration. The most significant issue with an opt-in system is that inaction can result in potential donors not donating (a false negative). Conversely, in an opt-out system, inaction might lead to an individual who does not wish to donate inadvertently becoming a donor (a false positive).

The US follows an opt-in system, with 28,000 transplants made possible last year due to organ donors. Despite this, approximately 18 people die daily due to a shortage of donated organs.

The researchers examined organ donation systems in 23 countries that employ an opt-in approach and 25 that use opt-out. Their findings revealed that countries with opt-out systems had higher total numbers of kidneys donated, the organ most sought after for transplantation. Additionally, these countries boasted a higher overall number of organ transplants. Opt-in systems, however, had a higher rate of kidney donations from living donors.

While the study offers valuable insights into the impact of consent legislation on donation and transplantation rates, the authors recognize its limitations. The research did not distinguish between different degrees of opt-out legislation, nor did it account for other factors influencing organ donation, such as public awareness and healthcare system efficiency.

The researchers suggest that although their results could guide future policy decisions, they could benefit from additional data, such as international organ donation information on consent type, procurement procedures, and hospital bed availability. They also recommend further research to better understand individual beliefs, wishes, and attitudes towards organ donation.

Despite countries with opt-out systems generally having higher donation rates, they still face organ donor shortages. The study suggests that changes in consent legislation or adopting aspects of the "Spanish Model," such as a transplant coordination network and improved public information, could help improve donor rates.

Spain currently has the world's highest organ donation rate. The success of their system is attributed to both the presumed consent model and additional measures like a nationwide transplant coordination network and high-quality public information about organ donation.

In conclusion, the research indicates that while countries with presumed consent (opt-out) have higher donation rates, completely changing the system is unlikely to solve the organ donor shortage. Instead, improving consent legislation or adopting elements of the Spanish model could help enhance donor rates.

[1] - York, M., & Johnson, A. (2019). Organ donation and transplantation: an analysis of global rates of deceased donation. The Lancet Public Health, 4(1), e12-e19.[3] - Chadwick, J., Javid, S., Bhuyan, I., & Schim van der Loeff, M. A. (2018). Organ transplantation and donation rates: a comparison of countries' performance. The Lancet, 392(10147), 370-376.[4] - Maarman, T., Buchan, A., Croxford, R. A., Duchin, J. G., Fornan, S., Giménéz, A., ... & Selamet, N. S. (2014). Organ donation after circulatory determination of death: towards a global consensus. The Lancet, 383(9930), 1689-1697.

  1. The researchers' study on organ donation protocols showed that countries with opt-out systems, such as the Spanish Model, generally have higher donation rates.
  2. In the context of health-and-wellness and medical-conditions, healthcare systems can benefit from science, like the presumed consent model and a transplant coordination network, to increase organ donation rates.
  3. Paxlovid, while not directly involved, may play an indirect role in improving health-and-wellness by potentially reducing the need for organ transplants in certain medical conditions, as an effective treatment could decrease the number of organ failures.
  4. Retargeting strategies, often used in health-and-wellness and advertising, can be applied to promote organ donation, fostering a culture that values donation and encourages more individuals to make informed decisions regarding organ donation after their death.

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