Over-the-counter male enhancements face withdrawal after testing positive for erectile dysfunction medications
A recently recalled supplement, ENDURANCE BOOST WITH HORNY GOAT WEED, poses significant risks for people taking nitrate medications commonly prescribed for heart disease or diabetes. The supplement, which was distributed solely online at US Amazon.com, has been found to contain Propoxyphenylsildenafil (a sildenafil analogue) and Sildenafil, undeclared ED drugs that can dangerously interact with nitrates.
The undeclared ED drugs, often PDE5 inhibitors like sildenafil, can interact with nitrates to cause severe and potentially life-threatening drops in blood pressure. When combined, this can lead to profound hypotension, resulting in symptoms such as dizziness, fainting, heart attack, or stroke.
While Horny Goat Weed itself contains icariin, a natural compound with mild PDE5 inhibitor-like effects, the danger arises from the undeclared synthetic ED drugs found in the recalled product, which are much more potent. The supplement’s marketed benefits on circulation and endurance do not reflect the risks posed by these hidden drugs.
EnShiShiXiangNiShangMaoYouXianGongSi, the company responsible for the product, is arranging for the return of all recalled products and has provided a return address: 150-67 Northern Blvd, Flushing, NY 11354. Consumers can contact the company via email at [email protected] for questions regarding the recall.
As of April 30, 2025, EnShiShiXiangNiShangMaoYouXianGongSi has not received any reports of adverse events related to this recall. However, consumers who have capsules with the specified lot number (LOT: 250214PRO) and expiration date (02/14/2027) should stop using the product immediately.
Adverse reactions or quality problems experienced with the use of this product can be reported to the FDA's MedWatch Adverse Event Reporting program. Consumers should also contact their physician or healthcare provider if they have experienced any problems that may be related to taking or using this drug product.
It is important to note that products containing sildenafil cannot be marketed as dietary supplements. Sildenafil is an ingredient in FDA-approved products for treating male erectile dysfunction. Adult males who use nitrates for cardiac conditions are most at risk from using ENDURANCE BOOST WITH HORNY GOAT WEED.
Medical experts strongly advise people with heart disease or diabetes taking nitrates to avoid such recalled supplements altogether and consult healthcare providers for safe alternatives.
- The undeclared ED drugs in ENDURANCE BOOST WITH HORNY GOAT WEED can interact dangerously with nitrates, posing risks for people with heart disease or diabetes on nitrate medications.
- This supplement, which markets benefits for health-and-wellness, circulation, and endurance, contains sildenafil, an ingredient in FDA-approved sexual-health treatments.
- In light of the potential risks, medical professionals urge people with heart disease or diabetes on nitrates to steer clear of such products and consult healthcare providers for safer alternatives in mental-health, nutritional, and therapies-and-treatments strategies.
