Unmasking Ozempic: The Ups and Downs of "Weight Loss Injection" Hype
Ozempic Explained: A Look at This Type 2 Diabetes Medication
Ozempic, the diabetes medication making waves, is receiving attention not just for its primary function but also for its secondary weight loss effects. Celebrities like Oprah Winfrey, Kathy Bates, and Elon Musk are known users. But what's the real deal about this so-called "weight loss injection"? ntv.de consulted two diabetologists to weigh in on the hype.
When Ozempic, when Wegovy? In Germany and the EU, Ozempic is solely approved for diabetes treatment, while Wegovy is used for weight loss.
First things first: "Ozempic is not a weight loss injection," clarifies Jochen Seufert, head of endocrinology and diabetology at the University Hospital Freiburg. "However, its weight loss effects can be significant as a side benefit." Despite millions using Ozempic and related medications for over two decades, side effects are rare. "These are valuable medications, and the benefits far outweigh the risks," agrees Jürgen Wagner, chief physician for internal medicine at the Stauffenburg Clinic.
Curbing Hunger
Ozempic uses semaglutide, which mimics hunger-suppressing hormones. It also slows down the gastrointestinal system, leading to reduced appetite and weight loss.
Little-Known Fact: Originally discovered in the 1980s, semaglutide, like the human GLP-1 hormone, was inspired by the saliva of the Gila monster, a desert lizard[5].
Common Side Effects
Common side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, stomach pain, and constipation. However, these symptoms often subside as the body adjusts[1][3]. There is also a risk of hypoglycemia when used with other diabetes treatments[1].
Rare but Potential Risks
While rare, potential side effects such as pancreatitis, kidney problems, vision changes, and gallbladder disease have been reported[1]. Furthermore, there may be a risk of kidney cancer, more commonly associated with related medications like Wegovy and Mounjaro[4].
Long-Term Concerns
Long-term effects may include mouth and dental issues due to reduced saliva production[2].
Off-Label Use and Accessibility
Since Ozempic isn't approved for weight loss, there may be concerns about its long-term safety and efficacy for this purpose[1]. Cost and availability can also be issues, with high costs and varying accessibility[1].
Maintaining a Balance
Gradual dose adjustment and lifestyle changes, including dietary adjustments and regular communication with healthcare providers, can help manage side effects[3].
A Word from the Experts: "This is a blessing, and theoritically, there might even be a Nobel Prize for it," says Seufert[6].
- Diabetes
- Medicines
- Diet
• Science played a significant role in the development of Ozempic, as semaglutide, the active ingredient in Ozempic, was originally inspired by the saliva of the Gila monster, a desert lizard, and was later synthesized in labs.
• In the health-and-wellness sphere, the use of medicines like Ozempic for weight management has gained popularity, but it's crucial to consider both the benefits, such as significant weight loss as a side effect, and the potential risks associated with long-term use and off-label use for weight loss, such as kidney cancer and high costs.
