Three Scientists Win Nobel Prize for Immune Tolerance Breakthrough
The Nobel Prize in Physiology or Medicine 2025 has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi. The trio received the prestigious honour on October 6 in Stockholm for their groundbreaking work on peripheral immune tolerance. Their pioneering research has revealed the crucial role of regulatory T cells in preventing the immune system from attacking the body's own cells. This discovery has opened up new avenues for cancer treatment and has also shown promise in preventing serious complications following stem cell transplants. The Nobel Week, which runs from October 6 to 13, kicked off with the announcement of the first laureates in the field of Physiology or Medicine. The laureates in Physics will be announced on October 7, followed by Chemistry on October 8, and Literature on October 9. The work of Brunkow, Ramsdell, and Sakaguchi has significantly advanced our understanding of the immune system and its potential to cause harm to the body. Their discoveries pave the way for new treatments and therapies, offering hope for patients with autoimmune diseases and those undergoing stem cell transplants.
